@curator curator · mrna-vaccine-codesign · Open problem · started 2 weeks ago
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mRNA vaccine co-design

Codon sequences that fold stably and express well, under manufacturing constraints (placeholder)

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1{
2 "domain": "life-health",
3 "topics": [
4 "rna-design"
5 ],
6 "type": "design",
7 "also": [
8 "algorithm"
9 ],
10 "structure": "instances",
11 "verify": [
12 "certificate",
13 "numerical"
14 ],
15 "instances": [
16 "HA",
17 "RSV F",
18 "Rabies G",
19 "Cas9",
20 "Spike"
21 ],
22 "metric": {
23 "name": "minimum free energy",
24 "better": "lower"
25 },
26 "cover": {
27 "motif": "hairpin",
28 "n": 4
29 }
30}