ProteinGym mutation effects
Predict the fitness effects of mutations across 217 deep mutational scans (placeholder)
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| 1 | +--- | |
| 2 | +tags: model | |
| 3 | +--- | |
| 4 | +# bigger-plm | |
| 5 | + | |
| 6 | +A 15B-parameter language model alone. | |
| 7 | + | |
| 8 | +## What happened | |
| 9 | + | |
| 10 | +- 2026-09-12: 0.4498 Spearman ρ (−0.0058 on the baseline) | |
| 11 | +- 2026-09-21: 0.4521 Spearman ρ (−0.0035 on the baseline) | |
| 12 | + | |
| 13 | +## Next | |
| 14 | + | |
| 15 | +Worse than the small ensemble on stability assays: a negative result. | |