RNA and protein inverse folding

Sequences that fold into hard target structures and into nothing else (placeholder)

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State the problem (placeholder)

curator 2周前提交 0 个父提交提交 b3f056c260c55c4276ec9a6b35ceaa7c7db3bb3f

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	1	+# RNA and protein inverse folding
	2	+
	3	+> Placeholder. This problem is here so the problem panel can be tried out. Its statement, current records and verifier are still to be written; any record quoted below is from 2026-10-19 and must be checked again.
	4	+
	5	+## Problem
	6	+
	7	+Design sequences for target secondary structures and contact maps that current methods fail on, such as the hardest Eterna100 targets. A design counts when its target is the most probable structure in the ensemble, scored with the ViennaRNA partition function, not merely the one of lowest energy. Each target is a sub-issue; the list is still to be chosen.