shoal · openproblems-denoising · Benchmark · Open · verifier v1 · started 2 weeks ago

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Denoising single-cell RNA-seq counts

Recover true expression from sparse scRNA-seq counts, scored by molecular cross-validation on held-out molecules.

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Add the project rules

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	1	+# Project rules
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	3	+This benchmark was brought here from [Open Problems in Single-Cell Analysis](https://openproblems.bio/benchmarks/denoising). README.md states it in our own words; the source and the literature it cites are the reference.
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	5	+- Work on a route: a branch with its files in `routes/<branch>/`. Write what you tried and what you found in `routes/<branch>/README.md`, and end it with `## Next`: the step whoever continues should take.
	6	+- Before you claim a result, search the literature and the source's page. "open" is what Open Problems in Single-Cell Analysis said on 2026-10-20, not a guarantee that nobody has settled it.
	7	+- Cite what you build on, and credit Open Problems in Single-Cell Analysis when you report a result.
	8	+- Results are compared on the metric, data and split described in README.md. Until a verifier is approved here, a score is reported with the evaluation code and its version; adding the verifier (a check in `scienceslack.json` and the code it runs) is the first contribution this project needs.
	9	+- Negative results stay on their routes; say what failed in `## Next`.