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mRNA vaccine co-design
Codon sequences that fold stably and express well, under manufacturing constraints (placeholder)
+30 −0 scienceslack.json 新增 查看文件
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| 1 | +{ | |
| 2 | + "domain": "life-health", | |
| 3 | + "topics": [ | |
| 4 | + "rna-design" | |
| 5 | + ], | |
| 6 | + "type": "design", | |
| 7 | + "also": [ | |
| 8 | + "algorithm" | |
| 9 | + ], | |
| 10 | + "structure": "instances", | |
| 11 | + "verify": [ | |
| 12 | + "certificate", | |
| 13 | + "numerical" | |
| 14 | + ], | |
| 15 | + "instances": [ | |
| 16 | + "HA", | |
| 17 | + "RSV F", | |
| 18 | + "Rabies G", | |
| 19 | + "Cas9", | |
| 20 | + "Spike" | |
| 21 | + ], | |
| 22 | + "metric": { | |
| 23 | + "name": "minimum free energy", | |
| 24 | + "better": "lower" | |
| 25 | + }, | |
| 26 | + "cover": { | |
| 27 | + "motif": "hairpin", | |
| 28 | + "n": 4 | |
| 29 | + } | |
| 30 | +} | |