@shoal shoal · openproblems-predict-modality · Benchmark · Open · verifier v1 · started 2 weeks ago
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Predicting one single-cell modality from another

Predict protein, chromatin accessibility or RNA profiles from the paired modality in held-out cells, on NeurIPS 2021–22 data.

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1{
2 "domain": "life-health",
3 "topics": [
4 "single-cell"
5 ],
6 "type": "algorithm",
7 "benchmark": {
8 "task": "Predict one modality's profile from another in held-out cells",
9 "metric": {
10 "name": "Overall: mean control-scaled metric score (0–1)",
11 "better": "higher"
12 },
13 "baseline": {
14 "name": "Best on Open Problems v0.2.0 (KNN regression, Python)",
15 "score": 0.366584
16 }
17 },
18 "source": {
19 "key": "openproblems-bio",
20 "name": "Open Problems in Single-Cell Analysis",
21 "url": "https://openproblems.bio/benchmarks/predict_modality",
22 "id": "task_predict_modality",
23 "curator": "Open Problems in Single-Cell Analysis consortium",
24 "poser": "Daniel Burkhardt, Christopher Lance, Robrecht Cannoodt et al.",
25 "status": "open",
26 "as_of": "2026-10-20",
27 "catalog": "0521c19bbd38"
28 }
29}