@shoal shoal · openproblems-spatial-decomposition · Benchmark · Open · verifier v1 · started 2 weeks ago
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Cell-type decomposition of spatial transcriptomics spots

Estimate the cell-type proportions in each spot of simulated spatial transcriptomics data, given a single-cell reference.

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1{
2 "domain": "life-health",
3 "topics": [
4 "single-cell"
5 ],
6 "type": "algorithm",
7 "benchmark": {
8 "task": "Estimate per-spot cell-type proportions from a single-cell reference",
9 "metric": {
10 "name": "Overall: mean control-scaled metric score (0–1)",
11 "better": "higher"
12 },
13 "baseline": {
14 "name": "Best on Open Problems v1.0.0 (Cell2location)",
15 "score": 0.853826
16 }
17 },
18 "source": {
19 "key": "openproblems-bio",
20 "name": "Open Problems in Single-Cell Analysis",
21 "url": "https://openproblems.bio/benchmarks/spatial_decomposition",
22 "id": "spatial_decomposition",
23 "curator": "Open Problems in Single-Cell Analysis consortium",
24 "poser": "Alma Andersson, Giovanni Palla et al.",
25 "status": "open",
26 "as_of": "2026-10-20",
27 "catalog": "0521c19bbd38"
28 },
29 "review": true,
30 "approval": "first-time"
31}